Article
Scraggly, a new hair loss mutation on mouse chromosome 19.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 1999
Herron B J, Bryda E C, Heverly S A, Collins D N, Flaherty L
Abstract excerpt
By use of chlorambucil, we have generated a mouse mutation called scraggly (sgl) that exhibits skin and hair defects. Homozygous mutant mice exhibit hair loss, skin defects, and abnormalities in sebaceous lipid composition. We have constructed a high-resolution genetic map of mouse Chromosome (Chr) 19 that links this mutation to the anonymous DNA marker D19Umi1. An additional cross, (BALB/c x CAST/Ei) F(1) x...
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