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Article

Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice.

Veterinary pathology - 1 Sept 2020

Vogel Peter, Ding Zhi-Ming, Read Robert, DaCosta Christopher M, Hansard Melissa, Small Daniel L, Ye Gui-Lan, Hansen Gwenn, Brommage Robert, Powell David R

Abstract excerpt

Mice with an inactivating mutation in the gene encoding asparagine synthetase domain containing 1 (ASNSD1) develop a progressive degenerative myopathy that results in severe sarcopenia and myosteatosis. ASNSD1 is conserved across many species, and whole body gene expression surveys show maximal expression levels of ASNSD1 in skeletal muscle. However, potential functions of this protein have not been previously...

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Identifiers

PMID: 32638637
DOI: 10.1177/0300985820939251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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