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Article

Aldose reductase gene polymorphisms and peripheral nerve function in patients with type 2 diabetes.

Diabetes care - 1 Aug 2004

Sivenius Katariina, Pihlajamäki Jussi, Partanen Juhani, Niskanen Leo, Laakso Markku, Uusitupa Matti

Abstract excerpt

OBJECTIVE: We screened the human aldose reductase (ALR) gene for DNA sequence variants in type 2 diabetic and nondiabetic subjects and investigated whether the previously reported and novel polymorphisms were associated with neurophysiologic deterioration and clinical peripheral neuropathy. RESEARCH DESIGN AND METHODS: The study population included 85 Finnish type 2 diabetic and 126 nondiabetic subjects. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15277434
DOI: 10.2337/diacare.27.8.2021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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