Article
Aldose reductase gene polymorphisms and susceptibility to diabetic nephropathy in Type 1 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association - 1 Feb 2000
Moczulski D K, Scott L, Antonellis A, Rogus J J, Rich S S, Warram J H, Krolewski A S
Abstract excerpt
AIMS: To investigate association and linkage between DNA sequence variants in the aldose reductase (AR) gene on chromosome 7q35 and diabetic nephropathy (DN) in Type 1 diabetes mellitus. METHODS: By sequencing the promoter region and 10 exons in eight DN cases and eight controls, a frequent bi-al...
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