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Article

Single nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a Chinese Han population.

Molecular carcinogenesis - 1 Oct 2012

Fan Weiwei, Zhou Keke, Hu Dezhi, Song Xiao, Zhao Yingjie, Chen Hongyan, Wei Qingyi, Chen Gong, Shi Jinlong, Du Guhong, Mao Ying, Lu Daru, Zhou Liangfu

Abstract excerpt

Matrix metallopeptidases (MMPs) play an important role in central nervous system tumor growth, invasion and spreading. The currently available data provide clear evidence for the involvement of MMP3 in the pathophysiology of glioma. The study aims to explore the association of single nucleotide polymorphisms (SNPs) across the MMP3 gene with glioma risk. Three haplotype tagging and additional two promoter SNPs...

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Source

Identifiers

PMID: 21853476
DOI: 10.1002/mc.20842

Genes

MMP3

Provenance

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