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Article

Association analysis of the DRD4 and COMT genes in methamphetamine abuse.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Aug 2004

Li Tao, Chen Chi-ken, Hu Xun, Ball David, Lin Shih-Ku, Chen Wai, Sham Pak C, Loh El-Wui, Murray Robin M, Collier David A

Abstract excerpt

We analyzed two polymorphisms in genes encoding proteins of the dopamine system, the Val158Met polymorphism in the catechol-O-methyltransferase gene and the 120-bp VNTR polymorphism in the promoter of the dopamine D4 receptor gene for association with methamphetamine abuse. We used a case/control design with 416 methamphetamine abusing subjects and 435 normal controls. All subjects were Han Chinese from Taiwan....

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Source

Identifiers

PMID: 15274053
DOI: 10.1002/ajmg.b.30024

Genes

COMT
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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