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Article

Human disorders of ubiquitination and proteasomal degradation.

Current opinion in pediatrics - 1 Aug 2004

Jiang Yong-hui, Beaudet Arthur L

Abstract excerpt

PURPOSE OF REVIEW: The goal of this review is to provide an overview of rapidly evolving information on a new group of genetic inborn errors affecting ubiquitination and proteasomal degradation of proteins and to suggest a classification scheme for these disorders. The relevant genes encode ubiquitin, ubiquitin enzymes (E1 and many E2s and E3s), deubiquitinating enzymes, proteasomal subunits, and substrates...

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Source

Identifiers

PMID: 15273504
DOI: 10.1097/01.mop.0000133634.79661.cd

Genes

BRCA1
BRCA2
UBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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