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Ubiquitin-protein ligase E3A (UBE3A) mediation of viral infection and human diseases.

Virus research - 2 Oct 2023

Chaudhary Pankaj, Proulx Jessica, Park In-Woo

Abstract excerpt

The Ubiquitin-protein ligase E3A, UBE3A, also known as E6-associated protein (E6-AP), is known to play an essential role in regulating the degradation of various proteins by transferring Ub from E2 Ub conjugating enzymes to the substrate proteins. Several studies indicate that UBE3A regulates the stabilities of key viral proteins in the virus-infected cells and, thereby, the infected virus-mediated diseases, even...

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Identifiers

PMID: 37541588
DOI: 10.1016/j.virusres.2023.199191
PMCID: PMC10430597

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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