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Article

Ribosomal P0 protein domain involved in selectivity of antifungal sordarin derivatives.

Antimicrobial agents and chemotherapy - 1 Aug 2004

Santos C, Rodríguez-Gabriel M A, Remacha M, Ballesta J P G

Abstract excerpt

The ribosomal stalk protein P0 is involved in the susceptibility to the antifungal sordarin derivatives, as reported for a number of Saccharomyces cerevisiae resistant mutants. Mammals and some lower eukaryotes are naturally resistant to these compounds. It is shown here that expression in S. cerevisiae of the ribosomal protein P0 from Homo sapiens and from other sordarin-resistant organisms results in a decrease...

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Identifiers

PMID: 15273103
DOI: 10.1128/AAC.48.8.2930-2936.2004
PMCID: PMC478497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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