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Complete DNA Sequences of Two Oka Strain Varicella-Zoster Virus Genomes

12 Sept 2008

Abstract excerpt

Varicella-zoster virus (VZV) is a herpesvirus and is the causative agent of chicken pox (varicella) and shingles (herpes zoster). Active immunization against varicella became possible with the development of live attenuated varicella vaccine. The Oka vaccine strain was isolated in Japan from a child who had typical varicella, and it was then attenuated by serial passages in cell culture. Several manufacturers...

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PMID: 18787000
DOI: 10.1128/jvi.00777-08

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