Article
Population diversity in batches of the varicella Oka vaccine.
Vaccine - 12 Apr 2011
Kanda R K, Quinlivan M L, Gershon A A, Nichols R A, Breuer J
Abstract excerpt
The Oka vaccine is a live attenuated vaccine for the prevention of varicella. Although the vaccine differs from the progenitor virus by over 40 mutations, only three of these are fixed, the rest being a mixture of the wildtype and the vaccine allele. To examine the extent of this variability between two of the three commercially available vaccine preparations, we analysed the vaccine/wildtype allele frequencies...
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