Article
Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.
Neuron - 5 Feb 2004
Nagy Gábor, Reim Kerstin, Matti Ulf, Brose Nils, Binz Thomas, Rettig Jens, Neher Erwin, Sørensen Jakob B
Abstract excerpt
Protein kinase A (PKA) is a key regulator of neurosecretion, but the molecular targets remain elusive. We combined pharmacological manipulations of kinase and phosphatase activities with mutational studies on the exocytotic machinery driving fusion of catecholamine-containing vesicles from chroma...
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