Article
Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene.
Developmental biology - 15 Nov 1997
Szucsik J C, Witte D P, Li H, Pixley S K, Small K M, Potter S S
Abstract excerpt
The patterning of the mammalian brain is orchestrated by a large battery of regulatory genes. Here we examine the developmental function of the Gsh-2 nonclustered homeobox gene. Whole-mount and serial section in situ hybridizations have been used to better define Gsh-2 expression domains within the developing forebrain, midbrain, and hindbrain. Gsh-2 transcripts are shown to be particularly abundant in the...
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