Article
Altered forebrain and hindbrain development in mice mutant for the Gsh-2 homeobox gene.
Developmental biology - 15 Nov 1997
Szucsik J C, Witte D P, Li H, Pixley S K, Small K M, Potter S S
Abstract excerpt
The patterning of the mammalian brain is orchestrated by a large battery of regulatory genes. Here we examine the developmental function of the Gsh-2 nonclustered homeobox gene. Whole-mount and serial section in situ hybridizations have been used to better define Gsh-2 expression domains within t...
Topics
- Animals
- Body Patterning
- Gene Expression Regulation, Developmental
- Gene Targeting
- Genes, Homeobox
- Homeodomain Proteins
- Homozygote
- Immunohistochemistry
- In Situ Hybridization
- Mice
- Mice, Knockout
- Mutation
- Oxygen
- Phenotype
- Prosencephalon
- RNA, Messenger
- Rhombencephalon
- Transcription Factors