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Article

Functional characterization of the placental fusogenic membrane protein syncytin.

Biology of reproduction - 1 Dec 2004

Chang Chingwen, Chen Po-Tsang, Chang Geen-Dong, Huang Chang-Jen, Chen Hungwen

Abstract excerpt

Syncytin is an envelope protein of the human endogenous retrovirus family W (HERV-W). Syncytin is specifically expressed in the human placenta and mediates trophoblast cell fusion into the multinucleated syncytiotrophoblast layer. It is a polypeptide of 538 amino acids and is predicted to be posttranslationally cleaved into a surface (SU) subunit and a transmembrane (TM) subunit. Functional characterization of...

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PMID: 15269105
DOI: 10.1095/biolreprod.104.033340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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