Article
Closely related mammals have distinct asialoglycoprotein receptor carbohydrate specificities.
The Journal of biological chemistry - 24 Sept 2004
Park Eric I, Baenziger Jacques U
Abstract excerpt
We recently reported that the rat asialoglycoprotein receptor binds oligosaccharides terminating with sialic acid (Sia) alpha2,6GalNAc. Despite a high percentage of identical amino acids in their sequences, orthologues of the asialoglycoprotein receptor (ASGP-R) in different mammals differ in their specificity for terminal Siaalpha2,6GalNAc. The recombinant subunit 1 of the ASGP-R from the rat (RHL-1 or rat...
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