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Shark New Antigen Receptor (IgNAR): Structure, Characteristics and Potential Biomedical Applications

8 May 2021

Abstract excerpt

Shark is a cartilaginous fish that produces new antigen receptor (IgNAR) antibodies. This antibody is identified with a similar human heavy chain but dissimilar sequences. The variable domain (VNAR) of IgNAR is stable and small in size, these features are desirable for drug discovery. Previous study results revealed the effectiveness of VNAR as a single molecule or a combination molecule to treat diseases both in...

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PMID: 34066890
DOI: 10.3390/cells10051140

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