Article
The Ashwell-Morell receptor.
Methods in enzymology - 1 Jan 2010
Grewal Prabhjit K
Abstract excerpt
The Ashwell-Morell receptor (AMR) of hepatocytes, originally termed the hepatic asialoglycoprotein receptor, was the first cellular receptor to be identified and isolated and the first lectin to be detected in mammals. It is one of the multiple lectins of the C-type lectin family involved in recognition, binding, and clearance of asialoglycoproteins. We recently identified endogenous ligands of the AMR as...
Topics
- Animals
- Genotype
- Hepatocytes
- Ligands
- Metabolic Clearance Rate
- Mice
- Models, Biological
- Receptors, Cell Surface
