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Article

Asialoglycoprotein receptor (ASGPR): a peculiar target of liver-specific autoimmunity

29 Oct 2012

Abstract excerpt

Asialoglycoprotein receptor (ASGPR) autoantibodies have been considered specific markers of autoimmune hepatitis (AIH). The exact mechanisms responsible for the development of these autoantibodies and leading to autoimmunity to this peculiar liver receptor remain elusive. Furthermore, loss of T cell tolerance to ASGPR has been demonstrated in patients with AIH, but it is poorly understood whether such...

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PMID: 26000135
DOI: 10.1007/s13317-012-0041-4

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