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Article

Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity.

Traffic (Copenhagen, Denmark) - 1 Aug 2004

Dinneen Jennifer L, Ceresa Brian P

Abstract excerpt

The amount of cell-surface Epidermal Growth Factor Receptor (EGFR) available to secreted ligand (EGF) dictates a cell's ability to mediate cell proliferation, differentiation or migration. Multiple factors regulate EGFR cell-surface expression including the rates of protein synthesis and protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15260830
DOI: 10.1111/j.1398-9219.2004.00204.x

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15260830-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity.PMID 15260830Read ↗

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