Article
Secretory phospholipase A2 induces dendritic cell maturation.
European journal of immunology - 1 Aug 2004
Perrin-Cocon Laure, Agaugué Sophie, Coutant Frédéric, Masurel Aurélie, Bezzine Sofiane, Lambeau Gérard, André Patrice, Lotteau Vincent
Abstract excerpt
High level of phospholipase A(2) (PLA(2)) activity is found in serum and biological fluids during the acute-phase response (APR). Extracellular PLA(2) in fluids of patients with inflammatory diseases such as sepsis, acute pancreatitis or rheumatoid arthritis is also associated with propagation of inflammation. PLA(2) activity is involved in the release of both pro- and anti-inflammatory lipid mediators from...
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