Article
Secretory phospholipase A2 pathway in various types of lung injury in neonates and infants: a multicentre translational study.
BMC pediatrics - 8 Nov 2011
De Luca Daniele, Capoluongo Ettore, Rigo Vincent
Abstract excerpt
BACKGROUND: Secretory phospholipase A2 (sPLA2) is a group of enzymes involved in lung tissue inflammation and surfactant catabolism. sPLA2 plays a role in adults affected by acute lung injury and seems a promising therapeutic target. Preliminary data allow foreseeing the importance of such enzyme in some critical respiratory diseases in neonates and infants, as well. Our study aim is to clarify the role of sPLA2...
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