Article
Reduced ocular dominance plasticity and long-term potentiation in the developing visual cortex of protein kinase A RII alpha mutant mice.
The European journal of neuroscience - 1 Aug 2004
Rao Yan, Fischer Quentin S, Yang Yupeng, McKnight G Stanley, LaRue Adrienne, Daw Nigel W
Abstract excerpt
The cAMP-dependent protein kinase (PKA) signalling pathway has been shown to play an important role in long-term potentiation (LTP) and depression (LTD), and ocular dominance plasticity in the visual cortex. In order to investigate further the involvement of individual PKA subunits in visual cortical plasticity, LTP and LTD in vitro and ocular dominance plasticity in vivo in the developing visual cortex were...
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