Article
Cyclic diguanylate (c-di-GMP) regulates Vibrio cholerae biofilm formation.
Molecular microbiology - 1 Aug 2004
Tischler Anna D, Camilli Andrew
Abstract excerpt
While studying virulence gene regulation in Vibrio cholerae during infection of the host small intestine, we identified VieA as a two-component response regulator that contributes to activating expression of cholera toxin. Here we report that VieA represses transcription of Vibrio exopolysaccharide synthesis (vps) genes involved in biofilm formation by a mechanism independent of its phosphorelay and DNA-binding...
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