Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A systematic analysis of the in vitro and in vivo functions of the HD-GYP domain proteins of Vibrio cholerae.

BMC microbiology - 25 Oct 2014

McKee Robert W, Kariisa Ankunda, Mudrak Benjamin, Whitaker Courtney, Tamayo Rita

Abstract excerpt

BACKGROUND: The second messenger cyclic diguanylate (c-di-GMP) plays a central role in bacterial adaptation to extracellular stimuli, controlling processes such as motility, biofilm development, cell development and, in some pathogens, virulence. The intracellular level of c-di-GMP is controlled by the complementary activities of diguanylate cyclases containing a GGDEF domain and two classes of c-di-GMP...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3',5'-Cyclic-GMP Phosphodiesterases
Share to Biofilms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholera

Share to Cyclic GMP

Share to Disease Models, Animal

Share to Locomotion

Share to Vibrio cholerae

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 25343965
DOI: 10.1186/s12866-014-0272-9
PMCID: PMC4212101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A systematic analysis of the in vitro and in vivo functions of the HD-GYP domain proteins of Vibrio cholerae.PMID 25343965Read ↗

c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and PhosphodiesterasesSemantic proximity Read ↗

Shigella flexneri Diguanylate Cyclases Regulate Virulence.Semantic proximity Read ↗

Transcriptome and phenotypic responses of Vibrio cholerae to increased cyclic di-GMP level.Semantic proximity Read ↗

Detailed analysis of c-di-GMP mediated regulation of csgD expression in Salmonella typhimurium.Semantic proximity Read ↗

Protein Containing the GGDEF Domain Affects Motility and Biofilm Formation in Vibrio cholerae and is Negatively Regulated by Fur and HapR.Semantic proximity Read ↗

Shigella's c-di-GMP specific PDEs Modulate Biofilm and Virulence PhenotypesSemantic proximity Read ↗

Phenotypic-genotypic analysis of GGDEF/EAL/HD-GYP domain-encoding genes in Pseudomonas putida.Semantic proximity Read ↗

Cyclic-diGMP signal transduction systems in Vibrio cholerae: modulation of rugosity and biofilm formation.Semantic proximity Read ↗

Cyclic diguanylate riboswitches control bacterial pathogenesis mechanismsSemantic proximity Read ↗

Systematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in Dickeya zeae EC1.Semantic proximity Read ↗

Cyclic diguanylate (c-di-GMP) regulates Vibrio cholerae biofilm formation.Semantic proximity Read ↗

Comparative analysis of diguanylate cyclase and phosphodiesterase genes in Klebsiella pneumoniae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.