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Article

Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling.

Molecular and cellular biology - 1 Aug 2004

Sock Elisabeth, Rettig Stefanie D, Enderich Janna, Bösl Michael R, Tamm Ernst R, Wegner Michael

Abstract excerpt

The high-mobility-group domain-containing transcription factor Sox11 is expressed transiently during embryonic development in many tissues that undergo inductive remodeling. Here we have analyzed the function of Sox11 by gene deletion in the mouse. Sox11-deficient mice died at birth from congenital cyanosis, likely resulting from heart defects. These included ventricular septation defects and outflow tract...

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Source

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Identifiers

PMID: 15254231
DOI: 10.1128/MCB.24.15.6635-6644.2004
PMCID: PMC444853

Genes

SOX11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling.PMID 15254231Read ↗

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