Article

Differential Expression of Members of SOX Family of Transcription Factors in Failing Human Hearts

2020-08-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The Sry-related high-mobility-group box (SOX) gene family, with 20 known transcription factors in humans, plays essential roles during development and in many disease processes. Several SOX proteins, e.g., SOX4, SOX11, and SOX9, are required for normal heart morphogenesis. SOX9 was shown to contribute to cardiac fibrosis in animal models. However, differential e...

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Literature Corpus work: 579d4e8e-17de-5c3c-a96b-8c3e008bc988
DOI: 10.21203/rs.3.rs-52488/v1

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