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Article

The conformation of the activation peptide of protein C is influenced by Ca2+ and Na+ binding.

The Journal of biological chemistry - 10 Sept 2004

Yang Likui, Prasad Swati, Di Cera Enrico, Rezaie Alireza R

Abstract excerpt

Previous studies have suggested that the conformation of the activation peptide of protein C is influenced by the binding of Ca(2+). To provide direct evidence for the linkage between Ca(2+) binding and the conformation of the activation peptide, we have constructed a protein C mutant in the gamma-carboxyglutamic acid-domainless form in which the P1 Arg(169) of the activation peptide is replaced with the...

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PMID: 15254039
DOI: 10.1074/jbc.M407304200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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