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Article

Associations between vitamin D, vitamin D receptor gene and the androgen receptor gene with colon and rectal cancer.

International journal of cancer - 15 Jun 2006

Slattery Martha L, Sweeney Carol, Murtaugh Maureen, Ma Khe-Ni, Caan Bette J, Potter John D, Wolff Roger

Abstract excerpt

The transcriptional activity of the vitamin D receptor (VDR) gene is regulated, at least in part, by the androgen receptor (AR) gene. We evaluate how the number of polyglutamine (CAG) repeats of the AR gene influence colorectal cancer in conjunction with vitamin D, sunshine exposure and VDR. Studies of colon (1,580 cases and 1,968 controls) and rectal (797 cases and 1,016 controls) cancer were used. Vitamin D...

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Source

Identifiers

PMID: 16425262
DOI: 10.1002/ijc.21791

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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