Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.

Physiological genomics - 4 Oct 2004

Menzaghi C, Ercolino T, Salvemini L, Coco A, Kim S H, Fini G, Doria A, Trischitta V

Abstract excerpt

Adiponectin is a circulating enhancer of insulin action that is secreted by the adipose tissue. In epidemiological studies, serum levels of this protein predict the risk of type 2 diabetes and cardiovascular events. Serum adiponectin levels have been associated with variants at the adiponectin (APM1) and PPARgamma2 loci and have also been linked to markers on 5p15 and 14q13. We investigated the role of these four...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adiponectin
Share to Blood Glucose
Share to Chromosomes, Human, Pair 14

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fasting

Share to Genetic Linkage

Share to Intercellular Signaling Peptides and Proteins

Share to Multigene Family

Source

Identifiers

PMID: 15252189
DOI: 10.1152/physiolgenomics.00122.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.PMID 15252189Read ↗

Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians.Semantic proximity Read ↗

Linkage of plasma adiponectin levels to 3q27 explained by association with variation in the APM1 gene.Semantic proximity Read ↗

Genetics of adiponectin.Semantic proximity Read ↗

Human genetics of adiponectin in the metabolic syndrome.Semantic proximity Read ↗

Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.Semantic proximity Read ↗

The genetics of adiponectin.Semantic proximity Read ↗

The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians.Semantic proximity Read ↗

The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome.Semantic proximity Read ↗

Adiponectin, type 2 diabetes and the metabolic syndrome: lessons from human genetic studies.Semantic proximity Read ↗

Association study and mutation analysis of adiponectin shows association of variants in APM1 with complex obesity in women.Semantic proximity Read ↗

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.Semantic proximity Read ↗

Genetic architecture of plasma adiponectin overlaps with the genetics of metabolic syndrome-related traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.