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Article

The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians.

European journal of human genetics : EJHG - 1 Mar 2006

Mackevics Vitolds, Heid Iris M, Wagner Stefanie A, Cip Paula, Doppelmayr Hildegard, Lejnieks Aivars, Gohlke Henning, Ladurner Günther, Illig Thomas, Iglseder Bernhard, Kronenberg Florian, Paulweber Bernhard

Abstract excerpt

Low concentrations of adiponectin, the protein product of the APM1 gene, have been reported to be associated with obesity and insulin resistance. However, contrasting results have been described on the genetic variability in APM1 and characteristics of the metabolic syndrome and adiponectin serum concentrations. In the present study, we investigated the association of the two most well-known SNPs of APM1 (+45T>G...

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PMID: 16418740
DOI: 10.1038/sj.ejhg.5201552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians.PMID 16418740Read ↗

Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians.Semantic proximity Read ↗

Common polymorphisms (single-nucleotide polymorphisms SNP+45 and SNP+276) of the adiponectin gene regulate serum adiponectin concentrations and blood pressure in young Finnish men.Semantic proximity Read ↗

Association of adiponectin gene polymorphism with adiponectin levels and risk for insulin resistance syndromeSemantic proximity Read ↗

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome.Semantic proximity Read ↗

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.Semantic proximity Read ↗

Polymorphisms +45T>G and +276G>T of the adiponectin gene does not affect plasma adiponectin level and carotid intima-media thickness in patients with diabetes mellitus type 2.Semantic proximity Read ↗

The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men.Semantic proximity Read ↗

Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.Semantic proximity Read ↗

An SNP in the adiponectin gene is associated with decreased serum adiponectin levels and risk for impaired glucose tolerance.Semantic proximity Read ↗

Association of the +45T>G and +276G>T polymorphisms in the adiponectin gene with insulin resistance in nondiabetic Greek women.Semantic proximity Read ↗

Association of adiponectin gene -11377C>G polymorphism with adiponectin levels and the metabolic syndrome in Thais.Semantic proximity Read ↗

Genetic effects of adiponectin on blood lipids and blood pressure.Semantic proximity Read ↗

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