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Article

Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate.

Nature neuroscience - 1 Aug 2004

Moqrich Aziz, Earley Taryn J, Watson James, Andahazy Mary, Backus Carey, Martin-Zanca Dionisio, Wright Douglas E, Reichardt Louis F, Patapoutian Ardem

Abstract excerpt

Tactile information is perceived by a heterogeneous population of specialized neurons. Neurotrophin receptors (the receptor tyrosine kinases, Trks) mark the major classes of these sensory neurons: TrkA is expressed in neurons that sense temperature and noxious stimuli, and TrkC is expressed in proprioceptive neurons that sense body position. Neurotrophin signaling through these receptors is required for cell...

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PMID: 15247919
DOI: 10.1038/nn1283
PMCID: PMC2693051

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Source receipt: pubmed, retrieved 7 Sept 2026.

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