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Article

The bud scar-based screening system for hunting human genes extending life span.

Annals of the New York Academy of Sciences - 1 Jun 2004

Chen Cuiying, Contreras Roland

Abstract excerpt

We developed a high-throughput screening system that allows identification of genes prolonging life span in the budding yeast Saccharomyces cerevisiae. The method is based on isolating yeast mother cells with an extended number of cell divisions as indicated by the increased number of bud scars on their surface. Fluorescently labeled wheat germ agglutinin (WGA) was used for specific staining of bud scars....

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PMID: 15247043
DOI: 10.1196/annals.1297.061

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WRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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