Article
Maturation of dendritic cells by bacterial immunomodulators.
Vaccine - 29 Jul 2004
Spisek Radek, Brazova Jitka, Rozkova Daniela, Zapletalova Katerina, Sediva Anna, Bartunkova Jirina
Abstract excerpt
Dendritic cells (DC) become fully functional upon maturation by various stimuli. We tested whether an immunostimulatory effect of clinically used immunomodulators (Luivac, Biostim, Ribomunyl, Imudon, Bronchovaxom) is caused by direct DC activation. We found that Luivac, Biostim and Ribomunyl have a very high DC stimulatory potential in vitro. The level of DC activation was comparable or higher than DC maturation...
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