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Article

CETP gene variation: relation to lipid parameters and cardiovascular risk.

Current opinion in lipidology - 1 Aug 2004

Boekholdt S Matthijs, Kuivenhoven Jan-Albert, Hovingh G Kees, Jukema J Wouter, Kastelein John J P, van Tol Arie

Abstract excerpt

PURPOSE OF REVIEW: Over the past decade lowering of low-density lipoprotein-cholesterol levels has been established as the foundation for preventing coronary artery disease, but substantial additional risk reduction remains to be gained by modifying risk factors other than low-density lipoprotein-cholesterol. Raising high-density lipoprotein-cholesterol levels by inhibiting activity of the cholesteryl ester...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15243211
DOI: 10.1097/01.mol.0000137226.54278.60

Genes

CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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CETP gene variation: relation to lipid parameters and cardiovascular risk.PMID 15243211Read ↗

Common variation in the CETP gene and the implications for cardiovascular disease and its treatment: an updated analysis.Semantic proximity Read ↗

Haplotype analysis of the CETP gene: not TaqIB, but the closely linked -629C-->A polymorphism and a novel promoter variant are independently associated with CETP concentration.Semantic proximity Read ↗

Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk.Semantic proximity Read ↗

Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease.Semantic proximity Read ↗

An increased coronary risk is paradoxically associated with common cholesteryl ester transfer protein gene variations that relate to higher high-density lipoprotein cholesterol: a population-based study.Semantic proximity Read ↗

Polymorphisms in the CETP gene and association with CETP mass and HDL levels.Semantic proximity Read ↗

A novel cholesteryl ester transfer protein promoter polymorphism (-971G/A) associated with plasma high-density lipoprotein cholesterol levels. Interaction with the TaqIB and -629C/A polymorphisms.Semantic proximity Read ↗

CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction.Semantic proximity Read ↗

Haplotype analyses of cholesteryl ester transfer protein gene promoter: a clue to an unsolved mystery of TaqIB polymorphism.Semantic proximity Read ↗

CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease.Semantic proximity Read ↗

Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy Spanish population.Semantic proximity Read ↗

Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study.Semantic proximity Read ↗

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