Article
Haplotype analysis of the CETP gene: not TaqIB, but the closely linked -629C-->A polymorphism and a novel promoter variant are independently associated with CETP concentration.
Human molecular genetics - 15 Jan 2003
Klerkx Anke H E M, Tanck Michael W T, Kastelein John J P, Molhuizen Henri O F, Jukema J Wouter, Zwinderman Aeilko H, Kuivenhoven Jan Albert
Abstract excerpt
The TaqIB polymorphism in intron 1 of the cholesteryl ester transfer protein (CETP) gene is associated with plasma CETP concentration, high-density lipoprotein cholesterol (HDL-C) and coronary artery disease (CAD). These associations are generally thought to arise from linkage disequilibrium between TaqIB and (an)other functional polymorphism(s). To identify putative functional sites, we investigated phenotypic...
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