Article
Common variation in the CETP gene and the implications for cardiovascular disease and its treatment: an updated analysis.
Pharmacogenomics - 1 Jun 2008
Dullaart Robin P F, Sluiter Wim J
Abstract excerpt
Human plasma contains cholesteryl ester transfer protein (CETP) which, besides other functions, enables the transfer of cholesteryl esters in plasma from high-density lipoproteins (HDL) towards triglyceride-rich lipoproteins, thereby contributing to lower HDL cholesterol. Variations in the CETP gene, including the intronic TaqIB polymorphism (rs708272), are common in the population. Although HDL cholesterol is...
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