Article
Magnetic-silica based nucleic acid extraction for Human Immunodeficiency Virus Type-1 drug-resistance testing in low viremic patients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jan 2010
Milia Maria Grazia, Allice Tizano, Gregori Gabriella, Mussino Stefano, Orofino Giancarlo, Bonora Stefano, Ghisetti Valeria
Abstract excerpt
Human Immunodeficiency Virus Type-1 (HIV-1) drug-resistance testing is challenging for viral loads below 1,000 copies/mL, but, according to HIV-1 guidelines, it should be considered for improving patient management and treatment options. High-recovery and high-purity extraction methods can enhance standard performances of HIV-1 genotyping assays based on direct full-population sequencing. Aim of the present study...
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