Article
The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily.
Molecular biology and evolution - 1 Oct 2004
Martin Rowena E, Kirk Kiaran
Abstract excerpt
The malaria parasite's chloroquine resistance transporter (CRT) is an integral membrane protein localized to the parasite's acidic digestive vacuole. The function of CRT is not known and the protein was originally described as a transporter simply because it possesses 10 transmembrane domains. In wild-type (chloroquine-sensitive) parasites, chloroquine accumulates to high concentrations within the digestive...
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