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Article

Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria.

Annual review of microbiology - 8 Sept 2020

Wicht Kathryn J, Mok Sachel, Fidock David A

Abstract excerpt

Understanding and controlling the spread of antimalarial resistance, particularly to artemisinin and its partner drugs, is a top priority. Plasmodium falciparum parasites resistant to chloroquine, amodiaquine, or piperaquine harbor mutations in the P. falciparum chloroquine resistance transporter (PfCRT), a transporter resident on the digestive vacuole membrane that in its variant forms can transport these...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32905757
DOI: 10.1146/annurev-micro-020518-115546
PMCID: PMC8130186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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