Article
No association of angiotensin-converting enzyme 2 gene (ACE2) polymorphisms with essential hypertension.
American journal of hypertension - 1 Jul 2004
Benjafield Adam V, Wang William Y S, Morris Brian J
Abstract excerpt
Recent intriguing findings from genetic linkage, knockout, and physiologic studies in mice and rats led us to conduct the first investigation of the novel angiotensin-converting enzyme 2 gene (ACE2) in human hypertension (HT). We genotyped four single nucleotide polymorphisms (SNP) (A-->G at nucleotide 1075 in intron 1, G-->A at nucleotide 8790 in intron 3, C-->G at nucleotide 28330 in intron 11, and G-->C at...
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