Article
Importance of quantitative genetic variations in the etiology of hypertension.
Kidney international - 1 Dec 2000
Smithies O, Kim H S, Takahashi N, Edgell M H
Abstract excerpt
Recent progress has been remarkable in identifying mutations which cause diseases (mostly uncommon) that are inherited simply. Unfortunately, the common diseases of humankind with a strong genetic component, such as those affecting cardiovascular function, have proved less tractable. Their etiology is complex with substantial environmental components and strong indications that multiple genes are implicated. In...
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