Article
Correlation of angiotensin-converting enzyme 2 gene polymorphisms with stage 2 hypertension in Han Chinese.
Translational research : the journal of laboratory and clinical medicine - 1 Dec 2007
Niu Wenquan, Qi Yue, Hou Shuqin, Zhou Wenyu, Qiu Changchun
Abstract excerpt
Experimental evidence indicates that angiotensin-converting enzyme 2 (ACE2), a homologue of human ACE, might negatively regulate the activated renin-angiotensin-aldosterone system (RAAS) and might function as a protective regulator in the pathogenesis of hypertension. However, association studies regarding ACE2 are sparse in the literature, with negative results in the majority of cases. Here we conducted an...
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