Article
In vitro antibacterial activity of fluoroquinolones against Porphyromonas gingivalis strains.
The Journal of antimicrobial chemotherapy - 1 Aug 2004
Eick Sigrun, Schmitt Andrea, Sachse Svea, Schmidt Karl-Hermann, Pfister Wolfgang
Abstract excerpt
OBJECTIVES: The objective of the study was to evaluate the in vitro activity of ciprofloxacin, gatifloxacin and moxifloxacin against 16 Porphyromonas gingivalis strains. METHODS: MICs of the quinolones were established by Etest and the agar dilution technique. Experiments focused on determination of the spontaneous mutation rate and the induction of resistant strains, using 0.25-fold MIC of antibiotic. Fragments...
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