Comparative in-vitro activity of new quinolones against clinical isolates and resistant mutants.

doi:10.1093/jac/29.1.41

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Article

Comparative in-vitro activity of new quinolones against clinical isolates and resistant mutants.

The Journal of antimicrobial chemotherapy - 1 Jan 1992

Rohner P, Peebo M, Lew D P, Auckenthaler R, Pechère J C

Abstract excerpt

The in-vitro activity of five new fluoroquinolones, WIN 57273, sparfloxacin, fleroxacin, temafloxacin and ciprofloxacin was determined against 543 recent clinical isolates and eight quinolone resistant strains derived by mutation and their five parent strains. WIN 57273 was the most active compou...

Topics

4-Quinolones
Anti-Infective Agents
Bacteria
Drug Resistance, Microbial
Humans
Microbial Sensitivity Tests
Mutation

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