Article
Quinolones: a class of antimicrobial agents
2001-09-30
Abstract excerpt
The fluoroquinolones are a series of synthetic antibacterial agents that are used in the treatment of a variety of bacterial infections. These agents inhibit the DNA gyrase, abolishing its activity by interfering with the DNA-rejoining reaction. The inhibition of the resealing leads to the liberation of fragments that are subsequently destroyed by the bacterial exonucleases. All fluoroquinolones accumulate within...
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Identifiers and source
- Literature Corpus work
- c6590559-afc6-561a-b339-c26af7a2fb8c
- DOI
- 10.17221/7883-vetmed