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Article

Spot shape modelling and data transformations for microarrays.

Bioinformatics (Oxford, England) - 22 Sept 2004

Ekstrøm Claus Thorn, Bak Søren, Kristensen Charlotte, Rudemo Mats

Abstract excerpt

MOTIVATION: To study lowly expressed genes in microarray experiments, it is useful to increase the photometric gain in the scanning. However, a large gain may cause some pixels for highly expressed genes to become saturated. Spatial statistical models that model spot shapes on the pixel level may be used to infer information about the saturated pixel intensities. Other possible applications for spot shape models...

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PMID: 15059816
DOI: 10.1093/bioinformatics/bth237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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