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Article

Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex.

The EMBO journal - 21 Jul 2004

Ishikawa Momoyo, Tsuchiya Daisuke, Oyama Takuji, Tsunaka Yasuo, Morikawa Kosuke

Abstract excerpt

The atomic view of the active site coupling termed channelling is a major subject in molecular biology. We have determined two distinct crystal structures of the bacterial multienzyme complex that catalyzes the last three sequential reactions in the fatty acid beta-oxidation cycle. The alpha2beta2 heterotetrameric structure shows the uneven ring architecture, where all the catalytic centers of 2-enoyl-CoA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crystallography, X-Ray

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Identifiers

PMID: 15229654
DOI: 10.1038/sj.emboj.7600298
PMCID: PMC514956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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