Article

Confrontation of AlphaFold2 models with cryo-EM and crystal structures enlightens alternate geometries of the CYP102A1 multidomain protein

2022-03-21

Abstract excerpt

Large range structural dynamics plays a critical role for the function of electron transfer proteins. This information is generally not available from crystallographic structures, while cryo-electron microscopy (cryo-EM) can provide some elements but frequently with a degraded spatial resolution. Recently, AlphaFold-based structural modelling was extended to the prediction of protein complexes. In this work, bacte...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 559cfaa3-d101-50d7-94b2-59e54e5d5ec4
DOI: 10.1101/2022.03.21.485149

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Confrontation of AlphaFold2 models with cryo-EM and crystal structures enlightens alternate geometries of the CYP102A1 multidomain proteinDOI 10.1101/2022.03.21.485149Read

Comprehensive Collection and Prediction of ABC Transmembrane Protein Structures in the AI Era of Structural BiologySemantic proximity Read

Comprehensive collection and prediction of ABC transmembrane protein structures in the AI era of structural biologySemantic proximity Read

Predicting multiple conformations via sequence clustering and AlphaFold2.Semantic proximity Read

Prediction of multiple conformational states by combining sequence clustering with AlphaFold2Semantic proximity Read

Structure Bioinformatics of Eight Human ATP Synthase Fo Subunits and Their AlphaFold3-Predicted Water-Soluble QTY AnalogsSemantic proximity Read

Accurate Protein Domain Structure Annotation with DomainMapperSemantic proximity Read

Improving AlphaFold2-based Protein Tertiary Structure Prediction with MULTICOM in CASP15Semantic proximity Read

Hidden alternative structures of proline isomerase essential for catalysis.Semantic proximity Read

A resource for improved predictions of Trypanosoma and Leishmania protein three-dimensional structureSemantic proximity Read

Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex.Semantic proximity Read

Practical outcomes from CASP16 for users in need of biomolecular structure predictionSemantic proximity Read

AFsample2: Predicting multiple conformations and ensembles with AlphaFold2Semantic proximity Read