Article
Mitochondrial "swirls" induced by oxygen stress and in the Drosophila mutant hyperswirl.
Proceedings of the National Academy of Sciences of the United States of America - 13 Jul 2004
Walker David W, Benzer Seymour
Abstract excerpt
Mitochondrial dysfunction and reactive oxygen species have been implicated in the aging process as well as a wide range of hereditary and age-related diseases. Identifying primary events that result from acute oxidative stress may provide targets for therapeutic interventions that preclude aging. By using electron microscopy, we have discovered a striking initial pattern of degeneration of the mitochondria in...
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