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Article

Regional alterations in neuronal activity in dystonic hamster brain determined by quantitative cytochrome oxidase histochemistry.

Neuroscience - 1 Apr 1998

Nobrega J N, Richter A, Jiwa D, Raymond R, Löscher W

Abstract excerpt

The neural mechanisms underlying idiopathic dystonia are currently unknown. Genetic animal models, such as the dt(sz) hamster, a model of idiopathic paroxysmal dystonia, may be helpful to providing insights into the pathophysiology of this common movement disorder. Recent metabolic mapping studies in the hamster model, using 2-deoxyglucose autoradiography, demonstrated altered 2-deoxyglucose uptake in motor areas...

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PMID: 9502259
DOI: 10.1016/s0306-4522(97)00470-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Regional alterations in neuronal activity in dystonic hamster brain determined by quantitative cytochrome oxidase histochemistry.PMID 9502259Read ↗

[3H]-2-deoxyglucose uptake study in mutant dystonic hamsters: abnormalities in discrete brain regions of the motor system.Semantic proximity Read ↗

Quantitative EEG analysis of depth electrode recordings from several brain regions of mutant hamsters with paroxysmal dystonia discloses frequency changes in the basal ganglia.Semantic proximity Read ↗

The electrical activity is impaired in the red nucleus of dt(sz) mutant hamsters with paroxysmal dystonia: an EEG power spectrum analysis of depth electrode recordings.Semantic proximity Read ↗

Marked regional disturbances in brain metabolism of monoaminergic neurotransmitters in the genetically dystonic hamster.Semantic proximity Read ↗

Alterations in spontaneous single unit activity of striatal subdivisions during ontogenesis in mutant dystonic hamsters.Semantic proximity Read ↗

Altered expression of preproenkephalin and prodynorphin mRNA in a genetic model of paroxysmal dystonia.Semantic proximity Read ↗

Neuropathological studies in a mutant hamster model of paroxysmal dystonia.Semantic proximity Read ↗

Regional brain cytochrome oxidase activity in beta-amyloid precursor protein transgenic mice with the Swedish mutation.Semantic proximity Read ↗

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Polyamines in a genetic animal model of paroxysmal dyskinesia.Semantic proximity Read ↗

Spontaneous remission of paroxysmal dystonia coincides with normalization of entopeduncular activity in dt(SZ) mutants.Semantic proximity Read ↗

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